The information under lists described adverse reactions, applying the next frequency classification:
– You have taken it according to the instructions offered with the medical professional or in the information offered with the medicine and
Regardless of whether your driving skill isn't impaired, you will be suggested to carry with you some proof which the medicine has been prescribed for you - a repeat prescription form or possibly a patient information leaflet within the pack is normally considered suited.
Naloxone must be administered cautiously to individuals who will be known, or suspected, for being physically depending on dihydrocodeine. In this kind of cases, an abrupt or comprehensive reversal of opioid effects may well precipitate pain and an acute withdrawal syndrome.
This isn't a whole list of side effects and others could happen. Call your physician for medical suggestions about side effects.
Sedative medicines which include benzodiazepines or associated drugs: The concomitant use of opioids with sedative medicines which include benzodiazepines or relevant drugs raises the risk of sedation, respiratory depression, coma and Demise as a consequence of additive CNS depressant result. The dose and period of concomitant use ought to be restricted (see section four.four).
Sử dụng dihydrocodeine thường xuyên trong thời kỳ mang thai có thể gây lệ thuộc thuốc ở thai nhi và dẫn đến hội chứng cai nghiện ở trẻ sơ sinh. Nếu phụ nữ mang thai cần sử dụng opioid trong thời gian dài, cần tư vấn bệnh nhân về nguy cơ hội chứng cai opioid ở trẻ sơ sinh và đảm bảo có get more info phương pháp điều trị thích hợp.
Pain connected with hyperalgesia has a tendency to be more diffuse than the pre-existing pain and less defined in excellent. Symptoms of hyperalgesia may possibly resolve with a reduction of opioid dose.
Drug withdrawal syndrome Before beginning treatment with any opioids, a discussion should be held with patients To place in position a withdrawal system for ending treatment with dihydrocodeine.
The analgesic effect of dihydrocodeine appears for being primarily due to father or mother compound. The oral bio availability of dihydrocodeine is 20% as a result of substantial initial move metabolism.
your skin, tongue or lips change blue, gray or pale (when you have black or brown skin, This can be much easier to see around the palms of the arms or soles of your toes)
The chance is larger in youngsters who're obese or have respiratory issues, or soon after specified surgical procedures (which includes tonsil/adenoid removal). Converse with your doctor or pharmacist about the risks and benefits of the medication.
Pethidine, tramadol and dextromethorphan (a standard ingredient in cough medicines) are opioids with a high chance of causing serotonin syndrome when applied with serotonergic antidepressants.
The dosage is based on the medical issue and reaction to treatment. Tend not to increase your dose or use this drug far more often or for longer than prescribed because your chance of side effects may possibly boost. Effectively prevent the medication when so directed.